Simultaneous Determination of Glycyrrhizin and Glycyrrhetic Acid in Plasma by High Speed Liquid Chromatography

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Simultaneous determination of glycyrrhizin, glycyrrhetic acid and glycyrrhetic acid mono-glucuronide in Shakuyaku-kanzo-to incubated with rat feces by semi-micro high-performance liquid chromatography.

A method for semi-micro high-performance liquid chromatography (HPLC) has been established for the simultaneous determination of glycyrrhizin (GL), glycyrrhetic acid (GA) and glycyrrhetic acid mono-glucuronide (GAMG) in incubation mixtures of rat feces with Shakuyaku-kanzo-to decoction (combination of licorice root and peony root). The analysis could be accomplished within 20 min with a TSKgel ...

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ژورنال

عنوان ژورنال: YAKUGAKU ZASSHI

سال: 1978

ISSN: 0031-6903,1347-5231

DOI: 10.1248/yakushi1947.98.11_1545